KEGG T01001: 3588

Homo sapiens (human): 3588

Entry

3588              CDS       T01001

Symbol

IL10RB, CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IBD25, IL-10R2, IL-10RB

Name

(RefSeq) interleukin 10 receptor subunit beta

K05135

interleukin 10 receptor beta

Organism

hsa Homo sapiens (human)

Pathway

hsa04060

Cytokine-cytokine receptor interaction

hsa04061

Viral protein interaction with cytokine and cytokine receptor

hsa04630

JAK-STAT signaling pathway

hsa05145

Toxoplasmosis

hsa05152

Tuberculosis

hsa05163

Human cytomegalovirus infection

Network

nt06167 Human cytomegalovirus (HCMV)
nt06518 JAK-STAT signaling

Element

N00415

IL10 family to Jak-STAT signaling pathway

N00416

HCMV vIL10 to IL10-JAK-STAT signaling pathway

Disease

H00286

Crohn disease

H00412

Hepatitis B

H01227

Inflammatory bowel disease (IBD)

Drug target

Ilodecakin:

D04505

Pegilodecakin:

D11200

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    3588 (IL10RB)
  09133 Signaling molecules and interaction
   04061 Viral protein interaction with cytokine and cytokine receptor
    3588 (IL10RB)
09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    3588 (IL10RB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    3588 (IL10RB)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3588 (IL10RB)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:hsa04050]
    3588 (IL10RB)
   04090 CD molecules [BR:hsa04090]
    3588 (IL10RB)
Cytokine receptors [BR:hsa04050]
Interleukin receptor families
  IL10/28 receptor family
   3588 (IL10RB)
CD molecules [BR:hsa04090]
Proteins
  3588 (IL10RB)

SSDB

Motif

Pfam:

Interfer-bind Tissue_fac fn3 XK-related MP_p6

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

21:33266367..33310182

AA seq 325 aa
MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR
IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV
EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN
LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG
CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE
DSESGKQNPGDSCSLGTPPGQGPQS

NT seq 978 nt +upstreamnt +downstreamnt
atggcgtggagccttgggagctggctgggtggctgcctgctggtgtcagcattgggaatg
gtaccacctcccgaaaatgtcagaatgaattctgttaatttcaagaacattctacagtgg
gagtcacctgcttttgccaaagggaacctgactttcacagctcagtacctaagttatagg
atattccaagataaatgcatgaatactaccttgacggaatgtgatttctcaagtctttcc
aagtatggtgaccacaccttgagagtcagggctgaatttgcagatgagcattcagactgg
gtaaacatcaccttctgtcctgtggatgacaccattattggaccccctggaatgcaagta
gaagtacttgctgattctttacatatgcgtttcttagcccctaaaattgagaatgaatac
gaaacttggactatgaagaatgtgtataactcatggacttataatgtgcaatactggaaa
aacggtactgatgaaaagtttcaaattactccccagtatgactttgaggtcctcagaaac
ctggagccatggacaacttattgtgttcaagttcgagggtttcttcctgatcggaacaaa
gctggggaatggagtgagcctgtctgtgagcaaacaacccatgacgaaacggtcccctcc
tggatggtggccgtcatcctcatggcctcggtcttcatggtctgcctggcactcctcggc
tgcttcgccttgctgtggtgcgtttacaagaagacaaagtacgccttctcccctaggaat
tctcttccacagcacctgaaagagtttttgggccatcctcatcataacacacttctgttt
ttctcctttccattgtcggatgagaatgatgtttttgacaagctaagtgtcattgcagaa
gactctgagagcggcaagcagaatcctggtgacagctgcagcctcgggaccccgcctggg
caggggccccaaagctag

DBGET integrated database retrieval system

pFad - (p)hone/(F)rame/(a)nonymizer/(d)eclutterfier! Saves Data!