KEGG T01001: 5788

Homo sapiens (human): 5788

Entry

5788              CDS       T01001

Symbol

PTPRC, B220, CD45, CD45R, GP180, IMD105, L-CA, LCA, LY5, T200

Name

(RefSeq) protein tyrosine phosphatase receptor type C

K06478

receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]

Organism

hsa Homo sapiens (human)

Pathway

hsa04514

Cell adhesion molecules

hsa04660

T cell receptor signaling pathway

hsa04666

Fc gamma R-mediated phagocytosis

hsa05132

Salmonella infection

hsa05340

Primary immunodeficiency

Disease

H00091

T-B+Severe combined immunodeficiency

H00413

Hepatitis C

Brite

KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    5788 (PTPRC)
   04666 Fc gamma R-mediated phagocytosis
    5788 (PTPRC)
09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    5788 (PTPRC)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5788 (PTPRC)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    5788 (PTPRC)
Enzymes [BR:hsa01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5788 (PTPRC)
Protein phosphatases and associated proteins [BR:hsa01009]
Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    5788 (PTPRC)
CD molecules [BR:hsa04090]
Proteins
  5788 (PTPRC)

SSDB

Motif

Pfam:

Y_phosphatase CD45 fn3 PTP_N PTP-SAK Tc-R-P Y_phosphatase3 PTPlike_phytase DSPc PTP-NADK GnsAB_toxin TM231

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

1:198638713..198757476

AA seq 1306 aa
MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPA
STFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSVQTPHLPTHADSQTPSA
GTDTQTFSGSAANAKLNPTPGSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAAL
PARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYL
YNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVP
PGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLE
PEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFH
NFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTT
KSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFR
VKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVLYK
IYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFLAEFQSI
PRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPR
KYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVV
VKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNA
FSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEA
QYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ
HIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINA
SFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK
QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISM
IQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQV
VKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEFDNEVDKVKQDAN
CVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS

NT seq 3921 nt +upstreamnt +downstreamnt
atgaccatgtatttgtggcttaaactcttggcatttggctttgcctttctggacacagaa
gtatttgtgacagggcaaagcccaacaccttcccccactggattgactacagcaaagatg
cccagtgttccactttcaagtgaccccttacctactcacaccactgcattctcacccgca
agcacctttgaaagagaaaatgacttctcagagaccacaacttctcttagtccagacaat
acttccacccaagtatccccggactctttggataatgctagtgcttttaataccacaggt
gtttcatcagtacagacgcctcaccttcccacgcacgcagactcgcagacgccctctgct
ggaactgacacgcagacattcagcggctccgccgccaatgcaaaactcaaccctacccca
ggcagcaatgctatctcagatgtcccaggagagaggagtacagccagcacctttcctaca
gacccagtttccccattgacaaccaccctcagccttgcacaccacagctctgctgcctta
cctgcacgcacctccaacaccaccatcacagcgaacacctcagatgcctaccttaatgcc
tctgaaacaaccactctgagcccttctggaagcgctgtcatttcaaccacaacaatagct
actactccatctaagccaacatgtgatgaaaaatatgcaaacatcactgtggattactta
tataacaaggaaactaaattatttacagcaaagctaaatgttaatgagaatgtggaatgt
ggaaacaatacttgcacaaacaatgaggtgcataaccttacagaatgtaaaaatgcgtct
gtttccatatctcataattcatgtactgctcctgataagacattaatattagatgtgcca
ccaggggttgaaaagtttcagttacatgattgtacacaagttgaaaaagcagatactact
atttgtttaaaatggaaaaatattgaaacctttacttgtgatacacagaatattacctac
agatttcagtgtggtaatatgatatttgataataaagaaattaaattagaaaaccttgaa
cccgaacatgagtataagtgtgactcagaaatactctataataaccacaagtttactaac
gcaagtaaaattattaaaacagattttgggagtccaggagagcctcagattattttttgt
agaagtgaagctgcacatcaaggagtaattacctggaatccccctcaaagatcatttcat
aattttaccctctgttatataaaagagacagaaaaagattgcctcaatctggataaaaac
ctgatcaaatatgatttgcaaaatttaaaaccttatacgaaatatgttttatcattacat
gcctacatcattgcaaaagtgcaacgtaatggaagtgctgcaatgtgtcatttcacaact
aaaagtgctcctccaagccaggtctggaacatgactgtctccatgacatcagataatagt
atgcatgtcaagtgtaggcctcccagggaccgtaatggcccccatgaacgttaccatttg
gaagttgaagctggaaatactctggttagaaatgagtcgcataagaattgcgatttccgt
gtaaaagatcttcaatattcaacagactacacttttaaggcctattttcacaatggagac
tatcctggagaaccctttattttacatcattcaacatcttataattctaaggcactgata
gcatttctggcatttctgattattgtgacatcaatagccctgcttgttgttctctacaaa
atctatgatctacataagaaaagatcctgcaatttagatgaacagcaggagcttgttgaa
agggatgatgaaaaacaactgatgaatgtggagccaatccatgcagatattttgttggaa
acttataagaggaagattgctgatgaaggaagactttttctggctgaatttcagagcatc
ccgcgggtgttcagcaagtttcctataaaggaagctcgaaagccctttaaccagaataaa
aaccgttatgttgacattcttccttatgattataaccgtgttgaactctctgagataaac
ggagatgcagggtcaaactacataaatgccagctatattgatggtttcaaagaacccagg
aaatacattgctgcacaaggtcccagggatgaaactgttgatgatttctggaggatgatt
tgggaacagaaagccacagttattgtcatggtcactcgatgtgaagaaggaaacaggaac
aagtgtgcagaatactggccgtcaatggaagagggcactcgggcttttggagatgttgtt
gtaaagatcaaccagcacaaaagatgtccagattacatcattcagaaattgaacattgta
aataaaaaagaaaaagcaactggaagagaggtgactcacattcagttcaccagctggcca
gaccacggggtgcctgaggatcctcacttgctcctcaaactgagaaggagagtgaatgcc
ttcagcaatttcttcagtggtcccattgtggtgcactgcagtgctggtgttgggcgcaca
ggaacctatatcggaattgatgccatgctagaaggcctggaagccgagaacaaagtggat
gtttatggttatgttgtcaagctaaggcgacagagatgcctgatggttcaagtagaggcc
cagtacatcttgatccatcaggctttggtggaatacaatcagtttggagaaacagaagtg
aatttgtctgaattacatccatatctacataacatgaagaaaagggatccacccagtgag
ccgtctccactagaggctgaattccagagacttccttcatataggagctggaggacacag
cacattggaaatcaagaagaaaataaaagtaaaaacaggaattctaatgtcatcccatat
gactataacagagtgccacttaaacatgagctggaaatgagtaaagagagtgagcatgat
tcagatgaatcctctgatgatgacagtgattcagaggaaccaagcaaatacatcaatgca
tcttttataatgagctactggaaacctgaagtgatgattgctgctcagggaccactgaag
gagaccattggtgacttttggcagatgatcttccaaagaaaagtcaaagttattgttatg
ctgacagaactgaaacatggagaccaggaaatctgtgctcagtactggggagaaggaaag
caaacatatggagatattgaagttgacctgaaagacacagacaaatcttcaacttatacc
cttcgtgtctttgaactgagacattccaagaggaaagactctcgaactgtgtaccagtac
caatatacaaactggagtgtggagcagcttcctgcagaacccaaggaattaatctctatg
attcaggtcgtcaaacaaaaacttccccagaagaattcctctgaagggaacaagcatcac
aagagtacacctctactcattcactgcagggatggatctcagcaaacgggaatattttgt
gctttgttaaatctcttagaaagtgcggaaacagaagaggtagtggatatttttcaagtg
gtaaaagctctacgcaaagctaggccaggcatggtttccacattcgagcaatatcaattc
ctatatgacgtcattgccagcacctaccctgctcagaatggacaagtaaagaaaaacaac
catcaagaagataaaattgaatttgataatgaagtggacaaagtaaagcaggatgctaat
tgtgttaatccacttggtgccccagaaaagctccctgaagcaaaggaacaggctgaaggt
tctgaacccacgagtggcactgaggggccagaacattctgtcaatggtcctgcaagtcca
gctttaaatcaaggttcatag

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